rac-Benzyl 3-oxohexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate was separated by chiral amino acids chromatography, and one of the enantiomers ([α]22D = +10°) was hydrogenated in the presence of Pd/C in methanol, producing octahydro-3H-pyrrolo[3,4-c]pyridin-3-one.The latter was reacted with (2R)-3,3,3-trifluoro-2-methoxy-2-p
Global participation in running continues to increase, especially amongst adolescents.Consequently, the number of Rice Bowl running-related injuries (RRI) in adolescents is rising.Emerging evidence now suggests that overuse type injuries involving growing bone (e.g., bone stress injuries) and soft tissues (e.g., tendinopathies) predominate in adole
New fossil vertebrates from the most representative Upper Pleistocene section (Tyrrhenian, MIS 5e) of the outcrop of San Giovanni di Sinis (Oristano, Sardinia) are here reported and described.The fossils, although scarce amino acids and fragmentary, document the occurrence of a terrapin (Mauremys sp.) and the endemic Sardinian deer (Praemegaceros c